摘要
目的 :研究神经妥乐平治疗急性缺血性脑卒中的可行性和有效性。方法 :对 5 0例发病4 8h内 ,神经功能评分 <80分 ,病灶面积 >2 .2 5cm2 的急性颈内动脉梗塞的患者进行随机分组试验 (神经妥乐平治疗组 31例 ,对照组 19例 )。测定治疗前后不同阶段神经功能缺损评分、日常生活能力、CT病灶面积和平均CT值 ,并进行统计学分板。结果 :治疗组神经功能改善率为 6 4.5 % ,对照组为 31.6 % ;11d时梗塞水肿面积治疗组已缩小 2 8.8% ,且平均CT值明显提高 ,改善程度明显优于对照组。结论 :neurotropin可作为治疗急性缺血性脑卒中和缺血性脑水肿的有效方法。
Objective: To study the feasibility and efficiency of neurotropin in treatment to patients with acute moderate and severe ischemic stroke.Method: Randome control trial of Neurotropin was performed in 50 patients admitted within 48h after acute internal carotid artery infarction.As neurological deficits score(Europe Stroke Scale,ESS) <80 and the area of infarct and edema area>2.25cm 2 all patients were divided in neurotropin group(31)and control group(19).we evaluated,ability of daily living(ADL)-Bar-thel index,and the size and average CT density of infarct and edema area. Result: The percentage of improved patients(complete and partial recovery)reaches 64.5% in the neurotropin group and 31.6% in the control group.The size of the infarct and edema area on CT scan significantly reduced only in the neurotropin group after treatment,which reduced to 28.8%on dll.the average CT density in the neurotropin group improved much more than in the control group.Conclusion: Neurtropin can be used as an effective therapy in acute ischmic stroke and ischemic cerebral edema.
出处
《河北医学》
CAS
2005年第1期53-56,共4页
Hebei Medicine
