摘要
目的:探讨中枢神经细胞瘤(CNC)的临床病理及影像学表现,以提高对该病的认识。方法:回顾性分析6例经手术病理证实为CNC的临床病理及影像学资料。结果:6例中男4例,女2例。年龄30～63岁,平均45岁。肿瘤位于侧脑室内的前中部及室间孔附近,呈宽基底紧贴侧脑室壁或透明隔。CT表现为等或稍高密度肿块,其内夹杂多个低密度小坏死灶或斑片状钙化灶。MR表现为T1WI等或稍低信号,T2WI不均匀稍高信号,增强后肿瘤轻、中度强化。免疫组化突触素(Syn)、胶质纤维酸性蛋白(GFAP)和神经元特异性烯醇化酶(NSE)标记均为阳性。结论:CNC主要发生在脑室前部或靠近室间孔附近,其影像学表现有一定的特征性,当此区发生肿瘤时,要考虑CNC的可能。
Objective To explore the clinicopathologic and the imaging features of central neurocytomaCNC in order to improve the diagnosis. Materials and Methods Six cases of CNC were analyzed retrospectively also correlate with pathological features. Results There were 4 males and 2 females and the age ranged from 30 to 63 years oldthe mean age was 45 years old. The tumors were primarily located in the lateral ventricles close to the foramina of Monra and attached to the lateral wall of the lateral ventricle or septum pellucidum with a broad base. CT scan displayed isointense or slightly hyperintense mass with multiple small cystic features and patch like calcifications. The tumors revealed isointense or slightly hypointense signal on T1WI and heterogeneous hyperintense signal on T2WI with slight to moderate enhancement. Results of immunohistochemical study were positive for synptophysinSyn glial fibrillary acid proteinGFAP and neuron specific enclaseNSE. Conclusion The tumors were mainly located in the anterior region of ventricles or close to the foramina of Monra and their imaging features were characteristic. CNC should be taken into consideration if tumor arises from the specific region.
出处
《中国临床医学影像杂志》
CAS
2004年第12期661-663,共3页
Journal of China Clinic Medical Imaging
