摘要
目的 :观察针刺治疗格林 巴利综合征的临床疗效 ,探讨针刺对该病的免疫调节机制。方法 :72例患者随机分为针刺治疗组 (37例 )和激素对照组 (35例 )。治疗组取穴以循经远取与局部近取相结合 ,辅以随证配穴 ;对照组口服强的松。同时以患者脑脊液和外周血液中免疫球蛋白的含量为指标 ,观察其治疗前后的动态变化。结果 :针刺组痊愈 1 6例 (43 2 4 % ) ,显效 1 1例 (2 9 73 % ) ,好转 8例 (2 1 62 % ) ,无效 2例 (5 41 % ) ,总有效 35例 (94 59% )。激素组痊愈 7例 (2 0 0 0 % ) ,显效 9例(2 5 72 % ) ,好转 1 6例 (45 71 % ) ,无效 3例 (8 57% ) ,总有效 32例 (91 43 % )。两组总有效率差异无显著性意义 ,而痊愈率针刺组高于激素组。脑脊液及血中的免疫球蛋白含量 ,两组治疗后均有下降 ,尤以激素组降幅明显。结论 :针刺治疗格林 巴利综合征疗效确切 ,具有抗异常免疫损伤和保护机体正常免疫功能的双重效应 。
ObjectiveTo observe the therapeutic effect of acup un cture on Guillain-Barre syndrome and explore immunoregulatory mechanisms of acu puncture in treatment of the disease. MethodsSeventy-two cases were randomly divided into treatment group ( n=37) and hormone control group (n=35). The treatment group were treated b y distal points selected along meridians in combination with local points, with adjuvant points used according to symptoms; the control group were treated by or al administration of prednisone. The contents of immunoglobulins in cerebrospina l fluid and peripheral blood were investigated before and after treatment. ResultsIn the acupuncture group, 16 cases (43 24%) were cured , 11(29 73%) markedly effective, 8(21 62%) improved, 2(5 41%) ineffectiv e, the total effective rate being 94 59% (35 cases); in the hormone control group , 7 cases (20 00%) were cured, 9(25 72%) markedly effective, 16(45 71%) imp roved, 3(8 57%) ineffective, the total effective rate being 91 43% (32 cases) with no significant difference between the two groups in the total effective rat e, but the cured rate in the acupuncture group was higher than that in the hormo ne control group; the contents of immunoglobulins in the cerebrospinal fluid and the peripheral blood in the two groups decreased, the decrease amplitude i n the hormone group being obvious. ConclusionAcupuncture has a definite therapeutic effect on Gui llain-Barre syndrome, and has the double effects of arresting abnormal immunolo gical injury and protecting normal immunological function, so as to exert immuno regulation.
出处
《中国针灸》
CAS
CSCD
北大核心
2003年第12期705-708,共4页
Chinese Acupuncture & Moxibustion
基金
江苏省中医管理局资助课题编号:9930
