摘要
目的 :探讨贺氏针法防治急性缺血性中风机理及其临床意义。方法 :将 50例急性脑梗死患者分为贺氏针法组 (观察组)和局部取穴组(常规组 )各 2 5例 ,分别观察针刺 2天、7天和 2 1天血浆组织型纤溶酶原激活物 (t PA)及快速抑制物 (PAI 1 )的活性 ,并与 2 0例脑梗死后遗症期住院患者(对照组 )进行对照。结果 :治疗后两组患者t PA活性降低又升高 (P <0 0 5)。观察组PAI 1活性升高又降低 ,与对照组比较差异无显著性意义 (P >0 0 5) ;常规组PAI 1活性降低又升高 ,且均明显高于对照组(P <0 0 5 ,P <0 0 1 )。结论 :贺氏针法对急性脑梗死患者血浆纤溶活性下降有一定的影响 。
Objective To explore the mechanism and clinical signifi ca nce of Hes needling method for treatment of acute ischemic apoplexy and pr event ion of thrombotic recurrence. Methods 50 cases of acute cerebral in f arction were divided into Hes needling method group (observation group) an d loca l point group (routine group), 25 cases in each group, and their plasma tissue t y pe plasminogen activator(t-PA) and plasminogen activator inhibitor-1(PAI-1) a ctivities were respectively investigated after acupuncture for 2, 7 and 21 days, w ith 20 inpatients of cerebral infarction at sequel stage used as control group. Results The t-PA activity on the second day of acute stage of cer ebral infarction decreased, and after treatment for 7 days the t-PA activities in both the observation group and the routine group increased (P<0 05). The PAI-1 activity on the 2nd day of acute stage increased and in the observation group on the 7th day decreased, with no significant difference compared with the control group (P>0 05); PAI-1 activity in the routine group on the 7th da y decreased and on the 21st day increased, which all were higher than those in t he control group (P<0 05,P<0 01). Conclusion Hes ne edlin g method can decrease plasma fibrinolytic activity in the patient of acute cereb ral infarction, and possibly has preventive action on recurrence of cerebral inf arction to a certain extent.
出处
《中国针灸》
CAS
CSCD
北大核心
2003年第11期681-683,共3页
Chinese Acupuncture & Moxibustion
基金
北京市科委课题(No 9540 2 4 1 1 0 )
关键词
贺氏三通法
急性脑梗死
血浆
T-PA
PAI-1
Acupuncture Therapy/meth
Brain Infarction/acup-mox the r
Brain Infarction/blood
