摘要
目的 研究巨细胞病毒活动性感染 (IgM阳性 )时婴幼儿肝功能指标的变化 ,及IgG阳性时 ,不同月龄的婴幼儿肝功能变化。方法 回顾性调查 2 0 0 1年～ 2 0 0 3年间 ,巨细胞病毒抗体 (IgM或IgG)阳性的婴幼儿肝功能指标的变化。结果 10 1例抗体阳性的婴幼儿中有 96例检查了肝功能 ,其中IgM阳性 35例 ,大部分肝功能指标均较正常值有所升高 ,其中AST升高最为显著。IgG阳性 6 1例 ,其中新生儿 2 4例 ,2 9d至 3个月 11例 ,4～ 6个月 14例 ,6个月以上至 2岁 12例 ,AST、ALT随年龄进行性升高 ,其余指标进行性下降。结论 AST可做为较敏感的CMV活动性感染及近期感染的指标。
Objective: To study the liver founction changes in infants with different age when CMV IgM or IgG antibody was positive . Methods: Retrospectively investigating liver founction indexs of infants with positive CMV IgM or IgG during 2001 to 2003. Results: 96 cases'liver founction were examined among 101 infants, most of liver founction indexs increased and AST was the most significant index in 35 cases with positive CMV IgM . Four groups among 61 cases with positive IgG were neonates(24 cases), infants with the age from 29 days to 3 months(11 cases) and from 4 months to 6 months (14 cases) and 6 months to 2 years (12 cases), AST and ALT were found increased with age, and other liver founction indexs decreased with age. Conclusion: AST was sensitive liver founction index for diagnosing CMV active and recent infection.
出处
《中国优生与遗传杂志》
2004年第6期110-111,共2页
Chinese Journal of Birth Health & Heredity
关键词
巨细胞病毒
婴幼儿
肝功能
Cytomegalovirus
Infants
Liver founction
