摘要
目的 :探讨可溶性干细胞因子 (SolubleStemcellfactorsSCF)在哮喘发病中的作用。方法 :使用酶联免疫吸附法对 90例哮喘患儿外周血发作期和缓解期血清sSCF的水平进行了检测。结果 :发现sSCF发作期水平较缓解期和正常对照组明显降低 (P均 <0 .0 1) ;缓解期水平有明显升高 ,但仍然低于正常对照组。结论 :sSCF参与了儿童支气管哮喘的发病 。
Objectives:To evaluate the effect of sSCF in pathogenesis of children with asthma. Methods: Serum sSCF was messured in 60 children with asthmatic acute attack, 30 children in asthmatic remission and 30 healthy controls by ELISA. Results: The level of sSCF was greatly decreased in asthmatic acute attacks and remission period. Conclusion: We suggest that sSCF may play a role in pathogenesis of children with asthma. It may serves as an important index in judging the severity of asthma in children.
出处
《青海医药杂志》
2004年第12期1-3,共3页
Qinghai Medical Journal
