摘要
①目的 观察美托洛尔对充血性心力衰竭 (CHF)的治疗效果。②方法 6 2例CHF病人随机分为 2组 ,治疗组 32例 ,对照组 30例 ,两组均给予强心、利尿、扩血管治疗 ,治疗组在此基础上加用美托洛尔 ,维持治疗6 0d后判断疗效。③结果 治疗组心功能改善情况优于对照组 (uc=2 .0 5 ,P <0 .0 5 ) ,超声心动图检测心脏各功能参数以及心率、血压均较治疗前有明显改善 (t =2 .2 8～ 8.96 ,P <0 .0 5 ,0 .0 1) ,且变化较对照组明显 (t =2 .17～2 5 .75 ,P <0 .0 1)。有 5例出现轻微副作用。④结论 美托洛尔治疗CHF效果确切 ,但应用时需严密监测血压、心率、ECG变化 。
Objective\ To investigate the therapeutic outcome of Metoprolol on congestive heart failure(CHF). Methods\ Sixty two patients with CHF were divided randomly into Control group(30 patients) and Metoprolol group (32 patients). A regular treatment was given to all patients. For Metoprolol group, Metoprolol was added for 60 days and the efficacy was compared with that of the Control group. \ Results\ In Metoprolol group, the improvement of heart function was better than that of the Control group ( u c=2.05,P <0.05). Echocardiography showed remarkable improvement in the parameters of heart function, heart rate and blood pressure compared with those of before therapy ( t=2.28-8.96, P <0.05,0.01), and the changes were more obvious than that of the Control group ( t= 2.17- 25.75, P <0.01). Slight side effects were noted in 5 patients. Conclusion\ The efficacy of Metoprolol for patients with CHF is definite . The blood pressure, heart rate and electrocardiographic changes should be monitored for the side effects.
出处
《青岛大学医学院学报》
CAS
2002年第2期174-175,共2页
Acta Academiae Medicinae Qingdao Universitatis
关键词
美托洛尔
心力衰竭
充血性
治疗结果
Metoprolol
heart failure, congestive
treatment outcome
