摘要
目的 探讨晚期卵巢癌理想肿瘤细胞减灭术的可行性。 方法 对 2 2例Ⅲ、Ⅳ期晚期卵巢癌患者行肿瘤细胞减灭术 ,手术中尽可能多地切除盆腹腔内原发或继发癌灶 ,清扫盆腔和腹主动脉旁淋巴结 ,其中 16例行理想肿瘤细胞减灭术 (残留灶 <2cm)。 结果 切除前≥ 2cm转移癌主要位于大网膜、盆腔和大肠 ;术后≥ 2cm的残留灶主要位于盆腔 ,其次在胃结肠韧带、肝门和脾门。术后平均随访 10 (2~ 14 )个月 ,达到理想手术的 16例均无复发 ,未达理想减灭术的 6例患者中复发及存活各 1例 ,死亡 3例 ,失访 1例。 结论 理想的肿瘤细胞减灭术对晚期及复发卵巢癌是安全可行的。
Objective To investigate the feasibility of maximum cytoreductive surgery for advanced ovarian cancer. Methods 22 cases of advanced ovarian cancer (stage Ⅲ or Ⅳ) underwent maximun cytoreductive surgery, in which the primary and secondery tumor-bearing lesion were resected maximally and periarotic and pelvic lymph nodes were dissected as well. The cytoreductive surgery was considered as a satisfactory operation when the residual lesion was less than 2 cm in diametre and sucessfully performed in 16 cases. Results The preoperative metastatic lesions with diametre over 2 cm were mainly located in ementum, pelvis and colon, the postoperative residual lesions with diametre over 2 cm were mainly located in pelvis and secondary at the gastrocolic ligment, hepatic hilum and splenic hilum. In accordence with the average 10(2~14) months follow-up, no recurrence occured in the 16 cases who underwent satisfied operation, the rest 6 cases demonstrated recurrence in 1 case, survive in 1 case, death in 3 cases and 1 case lost in follow-up. Conclusions Maximum cytoreductive surgery is feasible and effective for advanced and recurrent ovarian cancer.
出处
《中国现代手术学杂志》
2004年第6期345-347,共3页
Chinese Journal of Modern Operative Surgery