摘要
目的研究参藿口服液对动物免疫系统的影响。方法小鼠脾淋巴细胞增殖实验、小鼠溶血素(HC50)和单核巨噬细胞吞噬功能测定,小鼠皮肤迟发型过敏反应(DCH)实验。结果参藿口服液10～20mlkg连续口服6d,可显著促进小鼠脾淋巴细胞增殖反应,参藿口服液25～10mlkg连续口服6d,明显恢复免疫抑制小鼠单核巨噬细胞的吞噬活性和抗体产生能力,参藿口服液25～10mlkg连续口服10d,明显增强免疫抑制小鼠DCH反应,促进机体细胞免疫功能。结论参藿口服液能明显增强小鼠的体液免疫和细胞免疫功能。
Objective To study the effects of PEC, the oral liquid,which consists of Panax quinquefolium L, Epimedium brevicornum Maxim, Schisandra chinensis Bail and Cervus eplaphus L, on immune system in mice. Methods Lymphocyte proliferation assay and hemolysin concentration (HC 50 ) test were used,clearance rate of charcoal particles and DCH response induced by DNCB were determined. Results Application of 10-20 ml/kg of PEC promoted the lymphocyte proliferative activity, that of 2 5-10 ml/kg of PEC increased the production of serum specific antibody hemolysins, as well as it also enhanced clearance rate of charcoal particles, increased the phagocytic activity of the monocytes when it was given orally for 6-10 days. 2 5-10 ml/kg of PEC improved obviously the DCH response induced by DNCB in immune_suppression mice when it was given orally for 10 days. Conclusion PEC showed the strong immune_stimulating activities in mice.\;
出处
《中国比较医学杂志》
CAS
2004年第6期342-344,共3页
Chinese Journal of Comparative Medicine
