摘要
目的 探讨原发性肺癌胸内淋巴结转移特点及转移方式 ,为确定肺癌术中淋巴结廓清范围提供依据。方法 按Naruke肺癌淋巴结分布图作为淋巴结廓清标志 ,对 10 5例肺癌行完全性切除及系统性淋巴结廓清术。结果 10 5例肺癌 ,共清除淋巴结 80 1枚。N1占 15 .9% (5 9/3 71枚 ) ,N2 占 14 .9% (64 /4 3 0枚 )。跳跃性N2 共 12例 ,分布在纵隔第 2、4、5、6、7组淋巴结。肺原发肿瘤大小与淋巴结转移之间无明显关系。小细胞肺癌淋巴结转移率最高 ,腺癌淋巴结转移率亦高于鳞癌。肺癌淋巴结可呈跳跃式纵隔转移 ,且肺下叶癌较肺上叶癌多见。结论 肺癌淋巴结转移具有多组别、多区域及跳跃性特点 ,系统性胸内淋巴结廓清在肺癌术中应常规应用。
Objective To investigate the characteristics and patterns of lymph node metastasis in lung cancer, and to provide evidence for determining range of lymph node dissection. Methods One hundred and five patients with lung cancer received complete resection combined with systematic lymph node dissection according to the mapping system developed by Naruke. Results A total of 801 lymph nodes were dissected from 105 lung cancer patients. The positive ratios of N1 and N2 were 15.9% and 14.9%, respectively. Twelve patients were found with skipping N2. These skipping N2 were located in 2, 4, 5, 6, 7 groups respectively. There was no significant relationship between size of primary tumor and lymph node metastasis. Small cell lung cancer showed the highest risk of lymph node metastasis. The metastatic rate of lymph node in adenocarcinoma was markedly higher than that in squamous cell carcinoma. Skipping mediastinal lymphatic metastasis was found more frequently in lower lobar tumors than that in upper lobar ones. Conclusion Lymph node metastasis of lung cancer may occur in multiple groups and multiple regions, even in a skipping pattern. Systematic lymph node dissection should be routinely performed in pulmonary resection for lung cancer.
出处
《中国肺癌杂志》
CAS
2004年第6期508-511,共4页
Chinese Journal of Lung Cancer
关键词
肺肿瘤
肿瘤转移
淋巴结切除术
Lung neoplasms Neoplasm metastasis Lymphadenectomy
