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颈动脉狭窄的腔内介入治疗

Intravascular Interventional Therapy of Carotid Artery Stenosis
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摘要 目的 :评价颈动脉狭窄患者行腔内介入治疗的可行性与有效性。方法 :对 14 2例颈动脉狭窄患者的血管内介入诊疗资料进行回顾性分析。结果 :14 2例DSA检查均能获得明确的诊断 ,主要狭窄段位于颈总动脉 14例 ,颈内动脉 12 8例。狭窄段长度 8~ 6 5mm ,平均 14 .5± 2 .5mm。 38例颈动脉狭窄患者拟行腔内介入治疗者 ,37例成功地置入了血管内支架 ,1例患者因严重狭窄与扭曲 ,导丝无法通过而改行外科手术治疗。即刻DSA显示狭窄程度由术前的 78.7% (6 4 %~ 10 0 % )下降到约 32 .4 %(0~ 5 8% )。 2例患者在支架置入过程中出现短暂性脑缺血发作。在平均 6个月的随访中 ,无一例再发生短暂性脑缺血或脑梗死。结论 :腔内介入治疗是颈动脉狭窄患者安全有效的治疗手段。 Objective: To assess feasibility and efficacy of in travascular interventional therapy of carotid artery stenosis. Method s : 142 patients with stenosis of carotid artery (96 men, 46 women; age d 52-76Y; average age, 63.5±9Y) underwent selective DSA and percutaneous translu minal stenting were analyzed retrospectively. Results: All t he 142 patients who underwent selective DSA of carotid artery, could be diagnose d corretly. The lesions were in the common carotid artery in 14 patients and in the internal carotid artery in 128 patients. The lengths of the stenosis were fr om 8 to 65 mm. The stent placement was managed in the 37 cases successfully. In one patient, the lesion could not be crossed with a guidewire because of a sever ely stenosed and tortuous lesion. This patient was not a candidate for stent pla cement and was treated conservatively. The immediate DSA showed the average degr ee of stenosis of 78.7% (64%~100%) was reduced to an average of 32.4% (0~58%) . Two patients experienced transient ischemic attack (TIA ) during stent placeme nt. During a mean follow-up period of 6 months, there were no cases of TIA or ce rebral infarction. Conclusion: Intravascular intervention al therapy for patients with carotid artery stenosis is an effective and safe ther apeutic method with few and acceptable complications.
出处 《中国临床医学》 2004年第6期1137-1139,共3页 Chinese Journal of Clinical Medicine
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