摘要
目的 探讨幕上脑胶质瘤与脑内室管膜瘤的CT、MRI表现与病理肿瘤间质特性的相关性 ,为诊断治疗提供依据。方法 进行胶质瘤 (6 0例 )和室管膜瘤 (40例 )的CT和MRI配合MRPWI、MRS、MRA表现与手术病理(光镜和电镜 )超微结构和免疫组化对照研究。结果 胶质瘤和脑内室管膜瘤的CT和MRI显示的肿瘤形态不规则、分叶状、瘤壁及瘤结节、坏死囊变区、出血、瘤血管等表现 ,与手术病理肿瘤超微结构与肿瘤标记物表达相符合。结论 对胶质瘤和脑内室管膜瘤的间质生物学特性的CT、MRI研究 ,可提高预测肿瘤的病理分级的准确性 ,对临床实施抗肿瘤血管生成等多种方法配合手术治疗 ,对根治或控制肿瘤生长有帮助。
Objective To study the correlation of supratentorial gliomas and ependymoma between the features of pathology and the characteristic of CT,MRI and provide relevant data for diagnosis and treatment.Methods We analysised 60 patients with gliomas and 40 with ependymoma,contrasted their characteristic of CT,MRI with the features of pathology.Results The feature of irregular appearance,lobulation,tumor wall,tumor tubercle,necrotic cystiform zone,hemorrhage and tumor blood vessels were showed in CT and MRI,which was accord with the alteration of ultrastructure and the expression of tumous label.Conclusion Studying the morphology of supratentorial gliomas and ependymoma may be helpful to raise the veracity of pathologic grading,provide evidence to select treatment,operation and anti-vasoformation of the tumor etc.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2005年第1期61-62,共2页
Chinese Journal of Practical Internal Medicine