摘要
研究目的 小儿细菌性脑膜炎(菌脑)的病原构成及病原检测方法的阳性率比较。 研究方法 共53例,应用肺炎链球菌多价型(PNC)、流感嗜血杆菌B型(Hib)、脑膜炎双球菌A及B群(MCA,MCB)三种细菌抗血清,采用对流免疫电泳(CIE)检测脑脊液(CSF)、血、尿抗原共47例,CSF涂片革兰氏染色找细菌25例,CSF培养20例,血培养20例。 结果和结论 1.明确病原菌者86.7％,其中Hib占45.28％为主要病原菌,而MC28.3％占第二位,PNC占9.43％。2.检测方法中证明CIE检测抗原阳性率(89.4％)明显优于常规检查细菌的方法(15～35％),(P<0.01)。3.入院时第一次CSF,用CIE法检测病原阳性率最高。
Objective To determine bacterial constitution of children bacterial meningitis and positive rate of exa-mination method. Methods There are 53 patients The antigen of CSF were determind by PNC,HiB,MCA,MCB antibody,and of the blood and urine by CIE in 47 cases. CSF smear examinate bacteria in 25 cases. CSF culture in20 cases. blood culture 20 cases. Results and conclusions. 1. The rat: of definite pathogenic bacteria is 86.7% in 53 cases. Hib, MC, PNC are 45.2%,28.3%,9.43%, respectively. Hib is confirmed as one of primary pathogen. 2. To determine pathogenic bacteria, the positive rate of CIE(89.4%)is significantly higher than routinmethod (15～35%), (P<0.01). 3. The positive rate of first CSF at admitiou is significantly high by CIE.
出处
《实用儿科临床杂志》
CAS
CSCD
1993年第5期367-369,共3页
Journal of Applied Clinical Pediatrics
基金
WHO与国家自然科学基金
