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氟脲嘧啶经髂内动脉持续灌注加顺铂化疗联合放疗治疗浸润性膀胱癌 被引量:1

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摘要 目的:评估氟脲嘧啶经髂内动脉持续灌注加顺铂化疗联合放疗治疗浸润性膀胱癌的有效性及安全性。方法:对16例无法耐受或不愿意接受膀胱全切手术的浸润性膀胱癌患者进行保留膀胱治疗,包括氟脲嘧啶髂内动脉持续灌注加顺铂化疗联合放疗治疗。氟脲嘧啶每日1 000 mg,连用5 d,顺铂每日40 mg,连用3 d,平均放疗剂量为30-40 Gy。结果:经3次化疗,1个疗程的盆腔放疗,完全缓解率31.2%(5/16);部分缓解率44.4%(7/16);对部分缓解患者进行经尿道膀胱肿瘤切除术或膀胱部分切除术。所有病例定期随访,中位随访期为28.7个月。对随访期间发现的复发肿瘤再次行经尿道膀胱肿瘤切除术或膀胱部分切除。1例死于肿瘤。结论:氟脲嘧啶经髂内动脉持续灌注加顺铂化疗联合放疗治疗作为浸润性膀胱癌患者保留膀胱手术前新的辅助治疗,在提高生存率的同时可改善生活质量。
出处 《实用诊断与治疗杂志》 2005年第1期48-50,共3页 Journal of Practical Diagnosis and Therapy
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  • 1祝捷,吴海啸,邱建新,范昱,谭建明.髂内动脉灌注化疗联合放疗治疗浸润性膀胱癌[J].临床泌尿外科杂志,2004,19(2):83-84. 被引量:8
  • 2Kim H L,Steinberg. The current status of bladder presevation in the treatment of muscle invasive bladder cancer[J]. J Urol,2000,164:627. 被引量:1
  • 3Montie J E,Herr H W,Cookson M S. Against bladder sparing:surgery[J]. J Urol, 1999,162 : 452. 被引量:1
  • 4Vincenzo S,Giovanni L G,Carlo P, et al. The fate of patients with locally advanced bladder cancer treated conservativelywithneoad junant chemotherapy, extensive transurethral resection and radiotherapy: 10-year experience[J]. J Urol,1998, 159:1187. 被引量:1
  • 5Akimoto T,Matsunoto M,Nashimo T,et al. Radiation therapy and comcurrent daily intra arterial infusion of low-dose cisplatin following alteration of pelvic blood flow for invasive bladder caner:a preliminary report[J]. Anticancer Res, 1998,18 : 3731. 被引量:1

二级参考文献8

  • 1[1]Kim H L, Steinberg G D. The current status of bladder preservation in the treatment of muscle invasive bladder cancer. J Urol,2000,164:627-632. 被引量:1
  • 2[2]Montie J E, Herr H W, Cookson M S. Against bladder sparing: surgery. J Urol, 1999,162:452-458. 被引量:1
  • 3[3]Vincenzo S, Giovanni L G, Carlo P, et al. The fate of patients with locally advanced bladder cancer treated conservatively with neoadjunant chemotherapy, extensive transurethral resection and radiotherapy: 10-year experience. J Urol, 1998,159:1187-1190. 被引量:1
  • 4[4]Shipley W U, Kaufman D S, Zehr E, et al. Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancer. Urology, 2002,60:62-67. 被引量:1
  • 5[5]Sternberg C N, Pansadoro V, Calabro F, et al. Can patient selection for bladder preservation be based on response to chemotherapy? Cancer, 2003, 97:1644-1652. 被引量:1
  • 6[6]Takashima S, Nakamura K, Nakatsuka H, et al. Means of effective and practical intra-arterial chemotherapy for locally invasive bladder cancer--with special reference to clinical analysis of bladder cancer patients treated by intermittent intra-arterial infusion using an implantable port system. Act Urologica Japonica, 1999,45:127-131. 被引量:1
  • 7[7]Akimoto T, Matsunoto M, Nashimo T, et al. Radiation therapy and concurrent daily intra-arterial infusion of low-dose cisplatin following alteration of pelvic blood flow for invasive bladder cancer: a preliminary report. Anticancer Res, 1998, 18:3731-3735. 被引量:1
  • 8[8]Sumiyoshi Y, Hashine K, Karashima T, et al. Preliminary results of bladder preservation by concurrent intraarterial chemotherapy and radiotherapy for muscle-invasive bladder cancer. Int J Urol, 1998,5:225-229. 被引量:1

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