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B7家族的新成员—B7-H1、B7-H2、B7-H3、B7-DC 被引量:5

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摘要 T细胞的活化需要TCR与抗原肽 MHC的第一信号 ,以及共刺激因子的第二信号系统。B7家族是重要的共刺激分子 ,属于免疫球蛋白家族。除B7 1和B7 2外 ,近几年又发现了B7家族的新成员———B7 H1、B7 H2、B7 H3、B7 DC等 ,与T、B细胞的活化及免疫应答等有关。深入研究B7家族成员的结构和作用机制 ,有助于T、B细胞活化机制以及免疫耐受、肿瘤免疫研究的深入和发展。
出处 《国外医学(免疫学分册)》 2005年第1期41-43,共3页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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