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肺炎支原体感染并发传染性单核细胞增多症5例临床分析 被引量:2

A study on infectious mononucleosis with mycoplasma pneumoniae
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摘要 目的 :探讨小儿肺炎支原体 (MP)感染并发传染性单核细胞增多症 (传单 )的临床特征。方法 :对ELISA方法检测EB病毒 (EBV)、巨细胞病毒 (CMV)、疱疹病毒 (HHV)等IgM和PCR检测EBV -DNA均阴性 ,而MP -IgM和PCR检测MP -DNA均阳性的 5例传单患儿病历资料进行回顾性分析。结果 :5例均有发热、淋巴结肿大、咽峡炎、肝肿大 ,脾肿大 2例 ,咳嗽5例 ,鼻塞、眼睑浮肿 2例 ,腮腺肿大、皮疹 1例 ,肺部炎症、心肌损害 2例。 4例仅用阿奇霉素 ,1例仅用红霉素治疗 2周痊愈。结论 :MP感染可并发传染性单核细胞增多症 ,临床特征主要为不规则发热、淋巴结肿大、咽峡炎、肝脾肿大 ,阿奇霉素及红霉素治疗效果好。 Objective:To study the clinical features of infectious mononucleosis synsdrome due to mycoplasma pneumoniae in children.Methods:5 children with MP-IgM(+),PCR MP-DNA(+),EBV-IgM(-),CMV-IgM(-),HHV-IgM(-),EBV-DNA(-) were analyzed.All patients were diagnosed as infectious mononucleosis due to mycoplasma pneumoniae.Results:All the patients(100%) had fever,enlarged lymph nodes,angina and liver tumefaction.2 cases had spleen tumefaction;5 case had cough;2 cases had nasal obstruction and swollen blepharon;1 case had enlarged parotid gland and skin eruption,and 2 cases had pneumonia and myocarditis.4 cases were cured with azithromycin,and 1 case were cured with abomacetin for 2 weeks.Conclusion:Mycoplasma pneumoniae can lead to infectious mononucleosis syndrome.The main clinical features include irregular fever,angina,enlarged lymph nodes and hepatosplenomegaly.Azithromycin and abomacetin are effective for therapy.
出处 《重庆医科大学学报》 CAS CSCD 2004年第6期853-854,共2页 Journal of Chongqing Medical University
关键词 肺炎支原体 传染性单核细胞增多症 Mycoplasma pneumoniae Infectious mononucleosis
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  • 1胡亚美 江载芳.诸福棠实用儿科学[M](第7版)[M].北京:人民卫生出版社,2002.1199-1201. 被引量:395
  • 2王慕逖.儿科学[M](第4版)[M].北京:人民卫生出版社,1998.95-128. 被引量:20
  • 3Narita I, Yamada S, Nakayama T. Two cases of lymphadenopathy with liver dysfunction due to mycoplasma pneumoniae infection with mycoplasmal bacteraemia without pneumonia[J]. J Infect,2001 ;42(2): 154. 被引量:1

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