摘要
目的:探讨胸腺瘤及胸腺瘤合并重症肌无力的临床特征。方法:回顾分析1975年～2003年外科治疗的胸腺瘤318例资料,分为单纯胸腺瘤组(TT组)181例,胸腺瘤合并重症肌无力组(TTMG组)137例,对两组的一些临床特点进行分析对比。结果:TT组平均年龄36.2岁,最小年龄4岁,93.4%的患者肿瘤直径>5cm,病理分期多为Ⅲ、Ⅳ期(65.7%),手术切除率66.9%。TTMG组平均年龄46.2岁,最小20岁,肿瘤直径<5cm占67.9%,且59.8%为病理Ⅰ期,切除率86.1%。结论:早期胸腺瘤诊断标准为:1)肿瘤直径<3cm,2)临床病理分期Ⅰ期;胸腺瘤合并重症肌无力的特征:重症肌无力的症状重、病史短、症状进展快。
Objective: To present the clinic characteristics of thymoma and thymoma with myasthenia gravis (MG). Methods: Between 1975 and 2003, 318 cases of patients with thymoma (181 cases of thymus tumor, 137 cases of thymus tumor with myasthenia gravis) were surgically treated. Among the patients, 181 cases of thymus tumor (TT, GroupⅠ) were compared to 137 cases of thymus tumor with myasthenia gravis (TTMG, Group Ⅱ). Results: The average age for the patients in groupⅠwas 36.2, the youngest was 4 years old and the patients with diameter of tumors over 5cm accounted for 93.4%, and most of them (65.7%) were in the stage Ⅲ and Ⅳ of clinical pathology, the rate of operative resectability was 66.9%. In groupⅡ, the average age was 46.2, the youngest was 20 years old and the patients with the diameter of tumor under 5cm accounted for 67.9%, among which 59.8% were in the stageⅠof clinical pathology, the rate of operative respectability was 86.1%. Conclusion: The diagnostic standard of thymoma at early stage is that the diameter of tumor is below 3 cm. The clinical characteristics of TTMG includes the short history, the fast progress and serious of MG symptoms, the high incidence of thymus-crisis at postoperative.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2004年第22期1293-1295,共3页
Chinese Journal of Clinical Oncology
