摘要
目的 探讨急性创伤患者血清总胆固醇浓度变化与伤情判断及预后的关系。方法 监测我院急救创伤科2 0 0 4年收治的急性创伤患者入院时、出院时血清总胆固醇浓度及血糖、白细胞等其他指标 ,并与健康体检组对比分析。结果 好转或痊愈的急性创伤患者出院时血清总胆固醇浓度明显高于入院时 (P <0 0 1) ,血糖和白细胞总数也有显著性差异 (P值分别是 <0 0 1、<0 0 0 1) ,入院后并发感染或器官功能障碍仍需住院的患者血清总胆固醇浓度在较低水平波动。结论 急性创伤后出现低胆固醇血症 ,随病情缓解而改善 ,若低胆固醇血症持续或进一步加重 ,预示着感染 ,胆固醇是比白细胞更敏感的感染指标。急性创伤患者应连续监测血清胆固醇浓度。
Objective To assess the relationship between serum total cholesterol concentration and clinical outcomes in critically injured patients Methods During surgical intensive care unit (SICU) days, we measured 30 severe injury patients' white blood cell (WBC) count, cholesterol and glucose at admission and discharge, and compared with healthy group Results The convalescent patients had higher cholesterol at SICU discharge than at admission( P <0 01) The white blood cell and glucose had significant differences too( P <0 01,<0 001) Hypocholesterolemia persisted with onset of infection or organ dysfunction Conclusions Hypocholesterolemia is seen following critical injury Convalescing patients (ready for SICU discharge) have improved cholesterol levels. Decreasing or fixed cholesterol levels suggest the development of infection Cholesterol responses are more sensitive for the onset of infection than WBC responses Sequential cholesterol monitoring is recommended for patients with severe trauma [
出处
《中国急救医学》
CAS
CSCD
北大核心
2004年第12期871-872,共2页
Chinese Journal of Critical Care Medicine
关键词
急性创伤
胆固醇
血糖
白细胞
感染
Critical injury
Cholesterol
Glucose
White blood cell
Infection
