摘要
目的 探讨成人肺先天性囊性腺瘤样畸形 (CCAM)与肺癌的关系。方法 回顾性分析 5例成人CCAM临床病理特点 ,系统复习文献 ,对其病理分型、临床特点以及与肺癌的相关性进行讨论。结果 CCAMⅠ型 3例 ,Ⅱ型2例 ;1例伴有黏液型细支气管肺泡癌 ,1例伴有鳞癌 ,这 2例均可见上皮增生至恶性改变的移行过程。结论 CCAM患者有伴发肺癌的危险性。CCAM中出现的黏液细胞增生可能属于黏液型细支气管肺泡癌相对应的癌前病变 ,临床及病理医师均应提高对此病伴发肺癌危险性的认识。
Objective To study the correlation of congenital cystic adenomatoid malofrmation (CCAM) with lung cancer. Methods Five cases of CCAM in adults were analyzed retrospectively. The clinicopathologic presentation and correlation with lung cancer were discussed on the basis of a review of the literature. Results Three cases were CCAM Types Ⅰ, and 2 CCAM Types Ⅱ. One of them was associated with bronchioloalveolar carcinoma. Another case was associated with squamous cell carcinoma. A transition of epithelial hyperplasia into malignant change was observed in both cases. Conclusions Patients with CCAM are at increased risk of developing carcinoma and mucous cell hyperplasia possibly represents a premalignant lesion of mucinous type of bronchioloalveolar carcinoma.It is important for clinical physicians and pathologists to be aware of the risk of this entity.
出处
《诊断病理学杂志》
CSCD
2003年第5期284-286,i009,共4页
Chinese Journal of Diagnostic Pathology
