Construction and Analysis of N-phosphoryl Peptide Libraries
Construction and Analysis of N-phosphoryl Peptide Libraries
摘要
N-Phosphoryl peptide libraries were constructed by transformation from homo-oligopeptide libraries, which was synthesized by self-assembly of amino acids with the assistance of phosphorus oxychloride. Electrospray ionization mass spectrometry (ESI-MS) was used to monitor the reaction.
参考文献7
-
1[1]H. An, P. D. Cook, Tetrahedran Lett., 1996, 37, 7233. 被引量：1
-
2[2]N. Zhou, K. Lu, Y. Liu, et.al., Rapid Commun. Mass Spectrom., 2002, 16, 919. 被引量：1
-
3[3]Y. Pei, W. H. Moos, Tetrahedran Lett., 1994, 35, 5825. 被引量：1
-
4[4]C. J. Zhu, X. L. Yang, S. X. Cao, et al., Rapid Commun. Mass Spectrom., 2003, 17, 825. 被引量：1
-
5[5]Y. G. Shin, R. B. van Breemen, Biopharmaceutics & Drug Disposion, 2001, 22, 353. 被引量：1
-
6[6]Typical reaction produre: Homo-oligopeptide crude products were dissolved in 10 mL deionized water, 10 mL triethylamine, 5 mL ethanol and cooled in ice-salt bath to 0℃. 5 mmol DIPPH, 10 mL tetrachloromethane were added into the mixture and stirred for 3 hours. The mixture was extracted with ether(2×10 mL) and the water layer was adjusted to pH=3~4 with 1 mol/L hydrochloric acid in ice-salt bath,then fully extracted with ethyl acetate(5×10 mL). Oily liquids were acquired after removal of solvents. The gel column (Sephadex LH 20) loaded with crude library products was eluted with methanol to remove the impurities with less molecular weight. All fractions containing library compounds were collected to get more pure library products. 被引量：1
-
7[7]Y. Jiang, H. Fu, L. Xu, Q. Lu, J. Z. Wang, Y. F. Zhao, Rapid Commun. Mass Spectrom., 2000, 14, 1491. 被引量：1
-
1В.Я.Давыдов,赵振国.低聚肽分子结构与其薄层色谱R_M的关系[J].北京大学学报（自然科学版）,1992,28(2):178-184.
-
2曾华东,潘克桢.STUDIES OF RARE EARTH METAL COMPLEXES OF AMINO ACIDS AND PEPTIDES. SYNTHESES AND CRYSTAL STRUCTURES OF TRIAQUO TRIS (N-ACETYLGLYCINE) LANTHANIDE Ln(CH_3CONHCH_2COO)_3(H_2O)_3(Ln = Nd^(3+),Eu^(3+) and Er^(3+))[J].Chinese Journal of Structural Chemistry,1992,11(5):388-392.
-
3宗丽平,刘庆梅,李凌云.直接进样电喷雾质谱分析烷基苯磺酸盐[J].分析测试技术与仪器,2004,10(3):183-186. 被引量：9
-
4瞿金蓉,叶天秀.表面增强拉曼光谱测定缩氨酸在银表面上的取向[J].湖北工学院学报,2000,15(2):5-7. 被引量：2
-
5ZHANG Yonghong,LI Liangchun,YUAN Weicheng,ZHANG Xiaomei.Synthesis and Secondary Conformations of Homochiral β-Oligopeptides Containing Aryl Side Chains[J].Chemical Research in Chinese Universities,2015,31(3):381-387. 被引量：2
-
6Saburo Aimoto,Kenta Teruya,Koki Hasegawa,Takeshi Sato,Kenichi Akaji,Toru Kawakami.Recent Progress of Thioester Method[J].Chemical Research in Chinese Universities,2006,22(2):253-257.
-
7苏永波,司民真,张德清,刘仁明,李燕琼.大肠杆菌基于微波法制备的纳米银胶的SERS光谱研究[J].光散射学报,2012,24(4):351-354. 被引量：4
-
8杨成对,宋莉晖,张焱.表面活性剂的电喷雾质谱分析[J].分析测试学报,2008,27(10):1118-1120. 被引量：3
-
9Gu HE,Li GUO,Li Fang MA.Synthesis of Novel Dendrimers Containing Amino Acids and Peptides[J].Chinese Chemical Letters,2006,17(3):289-292.
-
10曹希传,李国栋,陈接胜,马淑杰,徐如人.140Cu/MCM-41和14T2Cu/MCM-41的制备与表征[J].高等学校化学学报,1999,20(1):25-27. 被引量：3
