摘要
目的 了解尿路感染病原菌的分布及耐药性 ,为临床提供可靠的诊断和治疗依据。方法 对 1999年 1月～ 2 0 0 3年 1月间 ,我院住院及门诊患者尿培养分离出的 10 7株细菌进行鉴定和耐药分析。结果 尿路感染菌株以大肠埃希菌为主 ,占 5 7.9%;其次为肠球菌属、变形菌属、肺炎克雷伯菌、铜绿假单胞菌、葡萄球菌属及真菌 ;肠杆菌科细菌除对亚胺培南保持 10 0 %敏感外 ,对其他抗生素耐药率均呈上升趋势 ;革兰阳性球菌耐药率也相当严重 ,仅万古霉素对革兰阳性球菌敏感率为 10 0 %。结论 尿路感染主要病原菌为肠杆菌科细菌 ,由于病原菌耐药性呈上升趋势 ,临床医师应根据尿培养结果合理使用抗菌药物。
OBJECTIVE To determine the bacterial distribution and resistance status in urinary system infections. METHODS A total of 107 strains collected from inpatient and outpatient urine specimens during Jan 1999-Jan 2003 were identified and the drug resistance test was performed. RESULTS Escherichia coli rated the top one (57.9%), followed with Enterococcus, Proteus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus and fungi. Enterobacteriaceae were showed increasing drug resistance trend, but still sensitive to imipenem (100%). G+-cocci were also showed serious drug resistance trend, but still sensitive to vancomycin (100%). CONCLUSIONS Enterobacteriaceae were the main infectious bacteria in urinary infection. Rational use of antibiotics should be carried out according to urine culture result.
出处
《中华医院感染学杂志》
CAS
CSCD
2004年第4期471-472,共2页
Chinese Journal of Nosocomiology
关键词
尿路感染
病原菌
抗菌药物
耐药性
Urinary system infection
Pathogens
Antibiotics
Drug resistance
