摘要
目的 研究中国新疆地区维吾尔族人群的FUT2基因分子结构。方法 对 4 0人份的维吾尔族人群随机供者血样进行DNA抽提 ,并进行FUT2基因测序分析。结果 共发现维吾尔族人群的FUT2有 35 7、385、4 2 8、7394处位置上存在突变 ,它们的基因频率分别为 :35 7T =71.2 5 % ,35 7C =2 8.75 % ,385A =77.5 0 % ,385T =2 2 .5 0 % ,4 2 8G =70 % ,4 2 8A =30 % ,739G =72 .5 0 % ,739A =2 7.5 0 %。结论 新疆维吾尔族人群的FUT2基因结构的特点提示新疆维吾尔族人群与台湾地区中国人和白种人间存在着一定程度的亲缘关系。
Objective To study the Secretor gene (FUT2) molecular structure of Uighur population in Xinjiang area,China. Methods DNA was extracted from 40 Uygur unrelated donors' blood and sequence analysis of FUT2 genes was performed. Results Four mutations in the FUT2 genes of Uighur donors have been identified. The frequencies of mutations were 71.25% for 357T, 28.75% for 357C,77.50% for 385A,22.50% for 385T,70% for 428G,30% for 428A,72.50% for 739G and 27.50% for 739A. Conclusion Based on the characteristics of FUT2 gene structure of Xinjiang Uighur,it cauld be thought that there are some relationships between Xinjiang Uighur, Taiwan Residents of China and Caucasiany.
出处
《中国输血杂志》
CAS
CSCD
2004年第5期306-307,共2页
Chinese Journal of Blood Transfusion
