摘要
目的:为了探讨偏头痛的发病机理。方法:用放免法测定了偏头痛病人发作期血浆TXB_2和6-Kito-PGF_1α的含量。结果:偏头痛发作期血浆TXB_2的含量明显低于对照组(P<0.01),6-Keto-PGF_1α的含量稍高于对照组,但无统计学差异(P>0.05)。结论:偏头痛病人发作期存在血浆TXB_2和6-Keto-PGF_1α的失衡,以血浆TXB_2的改变为主。
Objective To Study the mechanism of migraine .Method The content of plasma TXB_2 and 6 - Keto - PGF_1α in patients with migraine during the period of attack were assayed with ra- dioimmunoassay. Results The level of plasma TXB_2 was significant lower than that of the control group during the period attack in migraine patients(P<0.01). The level of plasma 6 - Keto - PGF_1α was higher than that of the control group, but there was no statistical difference(P>0.05)during the period of attack in those patients. Conclusion There was imbalance of dose of plasma TXB_2 and 6- Keto - PGF_1α in acute attack period of patients with migranie, the changes of dose of plasma TXB_2 was important.
出处
《河北职工医学院学报》
2000年第3期9-10,共2页
Journal of Hebei Medical College for Continuing Education