供体淋巴细胞输注防治白血病复发的研究进展
供体淋巴细胞输注防治白血病复发的研究进展
摘要
当前白血病治疗的最佳选择首先是采用联合化疗强烈杀灭白血病细胞取得完全缓解(CR)，有组织相容性白细胞抗原(Histocompatibility Leukocyte Antigen，HLA)匹配的相关性供髓者，再进行异基因骨髓移植(Allo-BMT)，这一方案确实能延长白血病患者的生存期，使大约50％的患者获得长期无病生存。然而许多患者最终还会因微量残留病灶(MBD)导致复发而死亡。
关键词
供体
淋巴细胞输注
防治
白血病
研究进展
自然杀伤
Leukemia/prevention and control
Donor
Lymphocytes
Infusions, intravenous /methods
Research
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