摘要
目的探讨一种新的改良超滤法在小儿体外循环术中的应用。方法按入选标准筛选出小儿先天性心脏病48例,随机分成A组(新法改良超滤组)和B组(标准改良超滤组),每组24例。观察两组病人的超滤液总量,不同时段的HCT,术后出血量、围术期用血量、血小板计数、心肌酶谱及呼吸机使用时间、ICU驻留时间、平均住院日。结果全组无死亡,术后恢复良好。A组超滤液总量、超滤后HCT较B组为高,而术后出血量、围术期用血量较B组为低,两组间有显著性差异(P<0.05);两组术后血小板计数、心肌酶谱、呼吸机使用时间、ICU驻留时间、平均住院日无显著性差异(P>0.05)。结论 新法改良超滤步骤简单,超滤效果进一步提高,临床应用安全、可靠、值得推广。
Objective To explore the clinical application of a new technique of modified ultrafiltration in pediatric cardiac operation with cardiopulmonary bypass. Methods 48 patients with congenital heart disease were selected on standard, and randomly divided into two group, group A (24 cases), with new modified ultrafiltration in CPB, group B (24 cases), with standard modified ultrafiltration in CPB. The total volume of ultrafiltration, perioperative HCT at specific intervals and transfusion requirement, postoperative blood loss, platelet counts, myocardial enzymes, duration of ventilator support, ICU stay and hospital stay were compared between two groups. Results No death occurred in all patients. The total volume of ultrafiltration and HCT after ultrafiltrating was increased, meanwhile the postoperative blood loss and perioperative transfusion requirement was significantly decreased in group A, as compared with group B (P<0.05). No significant difference was observed between group A and group B in platelet count, myocardial enzymes, ventilator support, ICU stay and hospital stay(P>0.05). Conclusions The new technique of modified ultrafiltration is simple and the efficiency of ultrafiltration might improve further. Clinical practice is safe, reliable. Therefore, the novel technique has value to popularize.
出处
《临床小儿外科杂志》
CAS
2002年第4期264-267,276,共5页
Journal of Clinical Pediatric Surgery
关键词
体外循环
心脏外科手术
超滤
Extracorporeal Circulation
Cardiac Surgical Procedures
Ultrafiltration
