摘要
用蝮蛇清栓酶治疗结缔组织病患者100例,并于治疗前后检测患者的血液流变学,血栓弹力图,血纤维蛋白原,TXB_2和6-k-PGF_1α。结果表明蝮蛇清栓酶治疗前结缔组织病患者均有血粘滞度增高,治疗后明显改善。临床疗效观察表明蝮蛇清栓酶对干燥综合征和硬皮病有一定的疗效,而对皮肌炎无效。
In 100 patients with connective tissue diseases were treated with Ancrod. Before and after the treatment, blood viscosity, platelet aggregation, thromboelastograph,plasma fibrinogen, TXB2 and 6-keto-PGF1α were assayed. The result showed that before the treatment, the blood viscosity increased in patients with connective tissue diseases, and significantly improved after the Ancrod therapy. Ancrod showed beneficial effect on the Sj8gren's Syndrome and Scleroderma, but no effect on the Dermatomyositis.
出处
《基础医学与临床》
CSCD
1993年第5期68-71,共4页
Basic and Clinical Medicine
关键词
蝮蛇清栓酶
血液流变学
胶原病
ancrod connective tissue diseases blood hemor heoalogy
