摘要
α-或β-硝基烷基膦酸酯双负离子与卤代烷反应,生成碳一烷基化产物,反应区域选择性取决于硝基膦酸酯的结构。讨论了可能的反应机理。
The reaction of dicarbanions derived from nitroalkylphosphonates with alkyl halides gave C-alkylation product. The regioselectivity of this reaction was depended on the structure of nitroalkylphosphonates. The reaction of dianion derived from α-nitroalkylphosphonates with alkyl halides afforded unique β-carbon-alkylation product. Whereas, with the dianion of β-nitroalkylphosphonates the alkylation reaction was occurred exclusive]y on the α-carbon atom adjacent to the phosphoryl group. Possible reaction mechanisms were discussed.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
1993年第10期1016-1022,共7页
Acta Chimica Sinica
基金
国家自然科学基金
