摘要
目的 :探讨乳腺癌术后胸壁局部复发因素及预后意义。方法 :对 73例乳腺癌术后胸壁复发患者进行回顾性分析。结果 :本组患者占同期全部乳腺癌病例的 4 0 2 % ,其中 5 0例 (6 8 5 % )胸壁复发发生在术后 2年内 ,复发后 34例 (4 6 6 % )于 2年内死亡。结论 :乳腺癌原发肿瘤分期晚、腋下淋巴结癌转移数多、复发率高 ;原发灶雌激素受体 (ER)及孕激素受体 (PR)阴性患者 ,复发多出现在术后 2年内。术后胸壁复发时 ,复发病灶情况及治疗效果是影响预后的因素之一 ,以手术为主的综合治疗可提高其远期疗效。
Objective:To explore the causes and prognostic factors of breast cancer with chest wall recurrence after operation.Methods:For 73 breast cancer patients with local recurrence on the chest wall,the clinical and pathological data were analyzed retrospectively.Results:the recurrence rate was 4.02%,the recurrence of 50 patients occurred within 2 years after operation and 34 patients died within 2 years after recurrence.Conclusion:The chest wall recurrence would occur in the patients with locally advanced stage and more positive axillary nodes.The recurrence would occur within 2 years after operation in patients with negative ER and PR of primary tumor.For the patients with local chest wall recurrence,the prognostic factors include the recurrence tumor and therapeutic efficacy.Synthetic therapy based on surgery can improve the long-term therapeutic efficacy.
出处
《四川肿瘤防治》
2004年第3期140-141,149,共3页
Sichuan Journal of Cancer Control
