期刊文献+

氧自由基对口腔粘膜损伤的动物实验研究(Ⅳ)——粘膜组织中生化指标的研究和综合分析 被引量:4

A Research on the Damage of Oxygen Free Radicals to the Oral Mucosa of Animal(Ⅳ)—Biochemical Observations
下载PDF
导出
摘要 为了解甲基紫精诱导的氧自由基造成口腔粘膜急性非特异性坏死性炎症的机制,对动物口腔粘膜组织进行了生化指标测定及综合分析,结果发现:随着氧自由基的产生,超氧化物岐化酶活性下降,并与氧自由基间呈指数曲线关系变化;氨基已糖升高,标志着粘膜固有层蛋白多糖分解增多。 In order to partly understand the mechanisms of morphological changes caused by oxygen free radicals(OFR) induced by paraquat(PQ),12 different enzymes were detected and observed by enzyme histological methods.Among them,6 locate on mitochondria,2 in cytoplasm,1 on lysosomes,and 3 on membrane structures individually.The results showed that the generation of OFR induced by PQ first came from the oxidation of NADPHD in cellu-lar structures.With the depletion of NADPH and increasing of OFR,the activity of these enzymes in cellular struc-tures decreased.The results indicated that these processes involved with the formation of inflammation and ulcerson the oral mucosa of hamster cheek pouch.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 1993年第2期138-141,共4页 West China Journal of Stomatology
基金 国家教委基金资助课题 编号C19005
  • 引文网络
  • 相关文献

参考文献5

二级参考文献8

共引文献20

同被引文献16

引证文献4

二级引证文献8

;
使用帮助 返回顶部