摘要
目的:研究马齿苋降血脂成分对高脂血症大鼠血脂的影响。方法:将大鼠分为4组:正常饲料组,正常饲料加马齿苋组,高脂饲料组,高脂饲料加马齿苋组,每组10只,喂养3周。于实验前后采血测大鼠血清总胆固醇)、高密度脂蛋白胆固醇(highdensitylipoprotein-C,HDL-C)并且根据公式计算低密度脂蛋白胆固醇(lowdensitylipoprotein-C,LDL-C)、动脉硬化指数。结果:实验前后正常饲料组大鼠血清总胆固醇(1.62±0.28)mmol/L、三酰甘油(0.39±0.24)mmol/L,HDL-C(1.30±0.18)mmol/L无变化;正常饲料加马齿苋组三酰甘油(1.40±0.26)mmol/L、总胆固醇(0.28±0.16)mmol/L降低,HDL-C(1.49±0.27)mmol/L升高;高脂饲料组总胆固醇(9.89±1.58)mmol/L、三酰甘油(3.12±0.35)mmol/L升高,HDL-C(1.05±0.29)mmol/L降低;高脂饲料加马齿苋组三酰甘油(4.10±1.45)mmol/L、三酰甘油(1.78±0.39)mmol/L比高脂饲料组低(P<0.01),HDL-C(1.59±0.36)mmol/L比高脂饲料组高(P<0.01)。结论:马齿苋对大鼠高脂血症有明显的预防作用。
AIM:To investigate the effect of the component of blood lipid reduction in Purslane on the level of blood lipid in rats with hyperlipemia.METHODS:The rats were divided into four groups:normal feeding group, normal feeding &Purslane group,high fat feeding group and high fat feeding &Purslane group with 10 in each group,and all rats were fed for three weeks.Blood was adopted to assay total cholesterol(TC), triglyceride(TG) and high density lipoprotein cholesterol(HDL C) before and after experiment.According to formula, the indexes of low density lipoprotein cholesterol(LDL C) and arteriosclerosis were measured.RESULTS:TC[(1.62±0.28)mmol/L],TG[(0.39±0.24)mmol/L]and HDL C[(1.30±0.18)mmol/L] of serum in rats were no changes before and after experiment in normal feeding group.TC[(1.40±0.26)mmol/L] and TG[(0.28±0.16)mmol/L]were decreased, but HDL C[(1.49±0.27)mmol/L] was increased in normal feeding &Purslane group.TC[(9.89 ±1.58)mmol/L] and TG[(3.12±0.35)mmol/L] were increased, but HDL C [(1.05±0.29)mmol/L] was decreased in high fat feeding group.TC[(4.10±1.45)mmol/L] and TG[(1.78±0.39)mmol/L] in high fat feeding &Purslane group were lower than those in high fat feeding group(P < 0.01),but HDL C[(1.59±0.36)mmol/L] was higher(P< 0.01).CONCLUSION:Purslane makes obviously protective effect on rats with hyperlipoemia.
出处
《中国临床康复》
CAS
CSCD
2004年第30期6678-6679,共2页
Chinese Journal of Clinical Rehabilitation
