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辨证与辨病相结合治疗非酒精性脂肪性肝炎的临床观察 被引量:7

A Clinical Observation on NASH by Treatment Based on Comprehensive Analysing Symptoms and Diseases
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摘要 目的 :观察按辨证与辨病相结合的方法应用中草药治疗非酒精性脂肪性肝炎的临床疗效。方法 :治疗组(60例 )采用辨证分型与辨病相结合的方法 ,用舒肝理气降脂方、化湿解毒降脂方、化痰祛湿降脂方、补气化瘀降脂方治疗 ;对照组 (2 0例 )用肝泰乐片、肌醇烟酸酯片治疗。两组均服药 8周 ,观察治疗前后ALT、GGT、TC、TG、B超或CT的变化 ,临床症状、体征的变化。结果 :治疗组的临床治愈率为 61 67% ,对照组为 3 0 0 0 %。P <0 0 1,差异有非常显著性意义。治疗组的总有效率为 91 67% ,对照组为 60 % ,P <0 0 5 ,差异有显著性意义。治疗组治疗前后ALT、GGT、TC、TG检测结果比较 ,P <0 0 1,差异有非常显著性意义。治疗后两组ALT、GGT等值比较 ,P<0 0 1,差异有非常显著性意义。结论 :辨证与辨病相结合的方法是治疗非酒精性脂肪性肝炎的有效方法 ,中草药有良好的降低血脂。 Objective:To observe the clinical therapeutic effect of Chinese Herbal Medicine for Nonalcoholic Steatohepatitis (NASH) based on an overall analysis of symptoms and an analysis of diseases. Methods:The sixty patients in the therapeutic groups were respectively treated with Shuganliqijiangzhi Mixture, Huashijiedujiangzhi Mixture, Huatangushijiangzhi Mixture and Bugihuayujiangzhi Mixture based on the comprehensive analysis of symptoms and diseases. The twenty patients in the control group were treated with Glucurolactone and Inositol Nicotinate tablets. The course of treatment was for eight weeks. The change of ALT, GGT, TC, TG, ultrasonography or CT, symptoms and signs before and after treatment were observed. Results:The clinical cure rate was 61.67% for the therapeutic groups and was 30.00% for the control group( P <0.05), the total effective rate was 91.67% for the former and was 60% for the latter( P <0.05), there was significant difference in the levels of ALT, GGT, TC, TG, before and after treatment( P <0.01). The levels of ALT, GGT,and etc. were apparently different between the two groups( P <0.01) after treatment. Conclusion:Chinese herbal medicine based on the comprehensive analysis of symptoms and diseases has good therapeutic effect. They can decrease the blood-fat and improve the hepatic function.
出处 《中西医结合肝病杂志》 CAS 2004年第5期272-274,共3页 Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
关键词 治疗组 辨病 降脂方 非酒精性脂肪性肝炎 对照组 辨证 ALT Nonalcoholic Steatohepatitis Syndrome Differentiation Analysis of Diseases Chinese Herbal Medicine Clinical Application
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