摘要
利用生物传热理论模型Pennes方程对Ar+激光辐照下生物组织的温度分布进行模拟研究;实验测定了离体猪鼻咽组织在Ar+激光(λ=488.0nm和514.5nm)辐照下不同位置的温度分布,重点研究了辐照功率密度和波长对组织中温度分布的影响。理论和实验结果表明:组织中的温度分布与组织不同深部位置、激光波长以及激光辐照功率密度有关;实验获得波长488nm和514.5nm的Ar+激光分别辐照鼻咽组织时安全光剂量分别为1.85W/cm2和1.72W/cm2。
The temperature distribution in nasopharynx tissue induced under the irradiation of rgon ion laser emitting at the wavelength of 488.0 nm and 514.5 nm were simulated by Pennes bioheat transfer equation.Furthermore,the dependence of measuring position,irradiation time and irradiation energy density,as well as wavelength on the temperature distribution was studied in detail.Simulation results and experimental results show that the temperature distributions in the porcine nasopharynx tissue were significantly affected by measuring position and the energy density and wavelength of irradiation laser.The safe dose of porcine nasopharynx tissue during the irradiation of argon ion laser at the wavelength of 488.0 nm and 514.5 nm is 1.85 W/cm^2 and 1.72 W/cm^2,respectively.
出处
《光电子．激光》
EI
CAS
CSCD
北大核心
2004年第10期1255-1259,1262,共6页
Journal of Optoelectronics·Laser
基金
国家自然科学基金资助项目(60178022)
福建省自然科学基金重大资助项目(2002F008)
