摘要
目的 探讨前列腺增生症合并急性尿潴留对血清前列腺特异性抗原 (PSA)浓度的影响。方法 回顾性分析 2 0 0 2年 10月至 2 0 0 3年 12月 16例 6 1～ 84岁的前列腺增生症合并急性尿潴留患者导尿前和留置尿管引流 1周后的血清PSA浓度 ,同期以需手术的前列腺增生症患者 5 1例术前血清PSA浓度为对照组 ,对比其血清PSA浓度的变化。结果 急性尿潴留组和对照组的血清PSA浓度分别为 19 5± 11 6 μg/L和 3 4± 2 2 μg/L ,两组间差异有非常显著意义 (t=14 2 6 ,P <0 0 0 1) ;16例急性尿潴留组 ,留置尿管引流 1周后血清PSA浓度较导尿前明显下降 (t=8 96 ,P <0 0 0 1)。结论 前列腺增生症合并急性尿潴留时血清PSA浓度明显升高 ,留置尿管引流
Objective To study the effect of acute urinary retention(AUR) in men with benign prostate hyperplasia(BPH) on the concentration of serum prostate specific antigen(PSA) elevation.Methods The serum PSA concentrations were measured in 16 men who had AUR with BPH immediately and one week after relief of urinary retention,and were compared with those of 51 men who did not have AUR with BPH at the same time before operations.The PSA concentrations measured before and after therapies in AUR group were also compared.Results The mean concentration of serum PSA in AUR group and non-AUR group were 19.5±11.6μg/L and 3.4±2.2μg/L respectively.The difference between the PSA concentrations of those two groups was significant(t=14.26,P<0.001).In AUR group the mean serum PSA levels of BPH patients declined to 7.1±6.2μg/L one week after relief of urinary retention.The difference was also significant(t=8.96,P<0.01).Conclusion Acute urinary retention in men with benign prostate hyperplasia could dramatically elevate serum PSA.But this elevation will gradually decrease to low levels one week after relief of urinary retention.
出处
《中国基层医药》
CAS
2004年第9期1067-1068,共2页
Chinese Journal of Primary Medicine and Pharmacy
