摘要
报告白细胞介素Ⅱ(IL-2)和淋巴因子激活杀伤细胞治疗中晚期肝癌31例,其中15例(A组)联合非典型性肝切除术,16例(B组)联合经股动脉插管化疗。随访7至14个月,A组全部健在,无肿瘤复发及转移,治疗后细胞免疫水平明显改善;B组平均生存期>5.84个月,其中10例肿瘤平均直径缩小2~6.2cm,细胞免疫水平有所改善。对免疫治疗以及联合手术、插管化疗的作用进行了讨论。
31 cases of advanced primary liver cancer were treated by using IL-2 and LAK cells in which 15 cases were combined with surgery (group A) and 16 cases were combined with chemotherapy (group B). 7~14 months follow-up showed: In group A there was no recurence and metastasis, and the cell-mediated immunity was obviously improved. In group B, the average life time was more than 5. 84months, the tumor average diameter dicreased in 10 cases, and the cell-mediated immunity was also improved. The role of immunotherapy combined with surgery or chemotherapy was discussed.