摘要
目的 :评价 1 %盐酸布替萘芬乳膏治疗浅部真菌病的临床疗效及安全性 ,并与 1 %联苯苄唑凝胶进行比较。方法 :对 83例浅部真菌病患者进行治疗 ,其中治疗组 43例 ,外用 1 %盐酸布替萘芬乳膏 ,每日 1次 ;对照组 40例 ,外用 1 %联苯苄唑凝胶 ,每日 1次 ,体股癣疗程 2周 ,手足癣 4周。分别于停药及停药 2周时观察记录患者的临床表现及治疗效果。结果 :1 %盐酸布替萘芬乳膏和 1 %联苯苄唑凝胶临床疗效相似 ,停药时临床总有效率分别为 90 7%和 90 0 % ,真菌总清除率为 93 0 %和 90 0 % ;停药 2周时临床总有效率分别为 97 7%和 92 5 % ,真菌总清除率为 1 0 0 0 %和 92 5 %。不良反应少。结论 :1
Objective:To evaluate the efficacy and safety of 1% butenafine hydrochoride cream in the treatment of superficial mycosis compared with 1% bifonazole gel. Methods:83 cases with superficial mycosis were devided into 2 groups. The study group ( n=43 ) were treated with butenafine hydrochoride cream and the control group (n=40) were treated by bifonazole gel for daily topical use. Tinea corporis and tinea cruris were treated for two weeks, tinea manus and tinea pedis were treated for four weeks. Results:The efficacy of 1% butenafine hydrochoride cream in the treatment of superficial mycosis was the same as 1% bifonazole gel. The effective rate was 90.7% and 90.0% respectively, mycological cured rate was 93.0% and 90.0% at the end of treatment. After another 2 weeks follow up, the effective rate was 97.7% and 92.5%, mycological cured rate was 100.0% and 92.5% respectively, and the side effect was few. Conclusion:1% butenafine hydrochoride cream is effective and safe in the treatment of superficial mycosis.[
出处
《岭南皮肤性病科杂志》
2004年第3期228-229,235,共3页
Southern China Journal of Dermato-Venereology
