摘要
目的 :观察卡托普利治疗慢性心力衰竭 (心衰 ) 16 8例临床疗效。方法 :采用随机对照临床试验方法 ,入选慢性心衰患者 16 8例 ,随机分成两组 ,即治疗组 84例 ,男 5 0例 ,女 34例 ,年龄 34～ 82岁 ,口服卡托普利及利尿剂 ,β受体阻滞剂 ,洋地黄类强心剂等治疗 ;对照组 84例 ,男 4 8例 ,女 36例 ,年龄 36～ 83岁 ,不用卡托普利 ,其它治疗同治疗组。结果 :随访半年治疗组患者病死率、再入院率明显低于对照组 (P <0 .0 5 ,0 .0 1) ;主观症状改善、左室射血分数提高 (P <0 .0 5 ) ;心功能分级明显高于对照组 (P <0 .0 5 ) ;两组住院天数无统计学差异。结论 :口服卡托普利有利于控制慢性心衰患者症状 ,改善心功能 ,提高患者生活质量。
Objection: To view the clinical effects of Captopril on chronic heart failure(CHF). Methods: One hundred sixty eight inclusive patients with CHF were divided into two groups randomly. Eighty-four patients with age from 34 to 82, including 50 males and 34 females, were in treatment group,and took Captopril besides of routine medicines such as Uretica,β receptor blocker, digitalis, and so on.The other 84 patients with age from 36 to 83, including 48 males and 36 females, were in controlled group,and also took all the medicines as that in treatment group except Captopril. Results:Mortality and rehospitalized rate during 6 months follow-up in treatment group were significantly lower(P<0.05,0.01); left ventricular ejection fraction(LVEF)and NYHA class improved(both P<0.05)though hospitalized days had no significant difference, compared with controlled group. Conclusion: The effects of Captopril are obvious on improving clinical condition, cardiac function, and life quality.
出处
《实用临床医学（江西）》
CAS
2004年第5期20-21,共2页
Practical Clinical Medicine
