摘要
目的 :观察救肝汤系列治疗慢性乙型肝炎的临床疗效。方法 :选符合诊断标准的慢性乙肝患者 6 2例 ,随机分为治疗组 32例 ,对照组 30例。治疗组根据证型选救肝汤 ～ 号口服 ,对照组单纯肌肉注射α- 2 a干扰素。均治疗 6个月。结果 :治疗组基本治愈 1例 ,有效 2 8例 ,无效 3例 ,总有效率为 90 .6 % (95 % CI=75 .0 %～ 98.1% ) ;对照组基本治愈 0例 ,有效 2 3例 ,无效 7例 ,总有效率为 76 .7% (95 % CI=5 7.7%～ 90 .1% ) ;两组综合疗效比较 ,无显著性差异 (u =1.115 0 ,P =0 .2 6 4 9) ;治疗组在改善症状和体征、恢复肝功能方面优于对照组。结论 :救肝汤系列在改善患者临床症状、恢复肝功能方面优于干扰素 ,在临床综合疗效方面与干扰素相当。收益 :OR=0 .34,NNT=7。
Objective:To observe the clinical effect of Jiugan decoction in treating chronic B Hepatitis.Method:62 patients with chronic B hepatitis were randomly divided into the treatment group(32 cases)treated with series of Jiugan decoction and the control group(30 cases)treated with α-2a interferon for 6 months.Result:In the treatment group,1 case cured,28 cases effective,3 cases ineffective,the total effective rate was 90.6%(95%CI=75.0%～98.1%);In the control group,non case cured,23 cases effective,7 cases ineffective,the total effective rate was 76.7%(95%CI=57.7%～90.1%).There was no significant difference between the two groups in comparision to the total effect (u=1.1150,P=0.2649).The treatment group was superior to the control group in improving symptoms and signs and reviving liver function.Conclusion:Jiugan decoction series was superior to interferon in improving symptoms and signs and reviving liver function.And had same effect as interferon in the total clinical effect.OR=0.34,NNT=7.
出处
《山西中医》
2004年第5期44-46,共3页
Shanxi Journal of Traditional Chinese Medicine
基金
宁夏回族自治区科学技术厅中标科研课题 (中标号 :2 0 0 2 -0 2 0 -11)
关键词
慢性乙型肝炎
救肝汤
临床研究
chronic B hepatitis
Jiugan decoction
clinical study
