摘要
目的 探讨Axsym全自动免疫分析仪MEIA法检测血清CA1 5- 3在乳腺癌诊断、监测及术后复发转移诊断中的临床意义。方法 采用微粒子酶免分析法 (MEIA)。结果 30例健康对照组血清CA1 5- 3含量平均为 (11.7± 5 .4 )U ml。 12 3例乳腺癌患者中 18例为术后复发或转移者 ,其血清CA1 5- 3含量均 >2 8U ml,阳性率为 10 0 % ;3例乳腺癌初诊时已发生转移者 ,血清CA1 5- 3均 >2 5 0U ml;10 2例为术后无复发转移者 ,其术后定期监测期间血清CA1 5- 3均 <2 8U ml。健康对照组与复发转移癌组比较有显著性差异 (P <0 .0 1) ,术后无复发转移者与术后复发转移者比较亦具有显著性差异 (P <0 .0 1)。结论 Axsym全自动免疫分析仪MEIA法检测血清CA1 5- 3在乳腺癌的诊断。
Objective To search for the clinical value of serum CA 15-3 for the diagnosis,supervision of breast cancer and diagnosis of afteroperation recurring and transfer of breast cancer with MEIA methods.Methods MEIA method was used in this study.Results The serum concentration of CA 15-3 in 30 control was (11.7±5.4)U/ml.The serum concentration of CA 15-3 in 123 patients including 18 cases with afteroperation recurring and transferring was more than 28U/ml and positive rate was 100%.The serum concentration of CA 15-3 in 3 cases with transeffing before seeing doctor was more than 250U/ml.The regularly monitoring serum concentration of CA 15-3 in 102 cases without recurring and transferring was less than 28U/ml.The difference of CA 15-3 between controls and cases with recurring and transferring was statistically significant and the statistical significance also was found between cases with afteroperation recurring and transferring and without afteroperation recurring and transferring.Conclusion The MEIA method with Axsym has significant clinical value in diagnosis,supervision of breast cancer and diagnosis of afteroperation recurring and transfer of breast cancer.
出处
《宁夏医学杂志》
CAS
2004年第10期637-638,共2页
Ningxia Medical Journal
