摘要
为了全面评价乙氰菊酯对鱼类的安全性,本实验研究了鲤鱼在不同浓度乙氰菊酯0.685、1.39、2.78、5.56mg/L(96hLC50的1/80、1/40、1/20、1/10)下曝露60d实验中,其行为、生长和血液生理生化指标所受到的不同影响。结果表明,与对照组相比,乙氰菊酯0.685、1.39mg/L处理对鲤鱼生长的影响差异性不显著,20d后2.78和5.56mg/L处理对鲤鱼生长的影响差异性显著(P<0.05);2.78和5.56mg/L处理组鲤鱼的行为和摄食受到一定影响,后期很少摄食,游动缓慢;5.56mg/L处理对鲤鱼生理生化指标的影响差异性极显著(P<0.01),2.78mg/L浓度组到染毒后期影响差异性显著,0.685mg/L处理影响差异性不显著。中毒鱼血红蛋白(Hb)量和红细胞(RBC)数量减少,表现出贫血;血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)活性升高;Na+浓度降低,表现为高血钾和低血钠症。高浓度试验组鲤鱼血液生化指标的变化与对照组间存在着显著(P<0.05)或极显著(P<0.01)差异;5.56和2.78mg/L处理组在实验结束时死亡率各为30%和20%。实验结果表明,鲤鱼长期曝露于较低浓度的乙氰菊酯药液中,其生长和生理生化指标均会受到一定影响。
To evaluate the security of cycloprothrin to cap thoroughly, the effects of different (concentration) cycloprothrin at 0.685、1.39、2.78 and 5.56 mg/L (1/10、1/20、1/40、1/80 of 96 h LC(50)) on the behaviour, growth and haematological biochemical indices of carp in 60 days were studied. The results showed that the concentrations of 0.685、1.39 had no effect on the growth of carp while the 2.78 mg/L and 5.56 mg/L concentration had obvious influence on the growth after being exposed for 20 days. The concentrations of 5.56、2.78 mg/L had effect on the behaviors as ate food less and swam slowly. The effect of haematological biochemical indices of carp was very (significant) under the concentration of 5.56 mg/L,and the concentration of 2.78 mg/L had effect on the indices (after) long term too. In the poisioned fish showed that the haemoglobin(Hb) (concerntration) and the red blood cell(RBC) numbers and the serum sodium level dropped; the serum alanine (aminotransferase)(ALT) and aspartate aminotransferase(AST) activity and serum potassium (level) raised. These haematological changes of the experimental groups were (different) significantly from the (control) group. The death rate of the (concentration) of 5.56、2.78 mg/L were 30 percent and 20 percent respectively. Results show, carp have been exposured in (correspondingly) low (concertration) cycloprothrin for a long term, its growth and haematological biochemical indices were been influenced.
出处
《农药学学报》
CAS
CSCD
2004年第3期56-61,共6页
Chinese Journal of Pesticide Science
基金
国家863课题(AA241170)资助.
关键词
乙氰菊酯
鲤鱼
亚慢性毒理
血液生理生化
cycloprothrin
carp
subchronic toxicology
haematological biochemical