摘要
动脉粥样硬化性肾血管病 (ARVD)是一种衰老性疾病 ,虽然可能没有临床症状 ,但它是弥漫性血管疾病的一种表现 ,许多ARVD患者出现肾外血管疾病的临床表现。ARVD是高血压和慢性肾功能衰竭 (CRF)常见原因 ,也是老年终末期肾功能衰竭 (ESRF)患者接受透析程序治疗的最常见肾病诊断之一。在这些患者中 ,肾损害的原因仍然是有争议的问题。ARVD患者死亡率高 ,尤其是那些有肾功能衰竭者。本文综述了相关的肾外血管疾病与ARVD之间的相互关系 ,以及对ARVD患者肾功能和死亡率的影响 ,同时也回顾了最新的ARVD患者肾功能不全的可能发病机制的有关证据。
Atherosclerotic renovascular disease (ARVD) is a disease of ageing. It is usually a manifestation of widespread cascular disease and although it may be symptomless, many patients with ARVD present with the effects of extra-renal vascular disease, such as peripheral vascular (PVD), coronary heart (CHD) and cerebrovascular disease. ARVD is a common cause of hypertension and chronic renal failure(CRF), and it is one of the most common renal diagnoses m elderly patients accepted on to dialysis program with end-stage renal failure (ESRF). The cause of renal impairment in these patients in still a matter of debate. Patients with ARVD have a high mortality, especially those with renal failure. In this review we examine the relationships between ARVD and co-morbid extra-renal vascular disease, and the impact of these associated vascular pathologies upon renal functional and mortality outcomes is considered. The latest evidence concerning the likely pathogenesis of renal dysfunction in patients with ARVD is also reviewed.
出处
《中国热带医学》
CAS
2004年第5期892-894,共3页
China Tropical Medicine
