摘要
分析神经元特异性烯醇化酶 (NSE)含量与流行性乙型脑炎 (乙脑 )患儿脑损伤程度的关系 ;探讨NSE在乙脑发病机制中的作用。方法 采用双抗体夹心法检测NSE含量。结果 乙脑患儿血清及脑脊液中NSE含量在初期即有增高 ,极期达高峰 ,恢复期下降。比较各型乙脑患儿血清及脑脊液中NSE含量 ,显示初期和极期差异有显著统计学意义 (P <0 .0 1 ) ,恢复期差异有统计学意义 (P <0 .0 5 )。结论 NSE含量的测定对乙脑患儿脑损伤程度的判断有重要的参考价值。
Objective To analyze the relationship between neuron-specific enolase(NSE) levels and extents of cerebral injury in patients with epidemic encephalitis B, and to study the use of NSE in the pathogenetic of epidemic encephalitis B. Method The NSE contents were measured by double antibody sandwich assay. Results NSE contents in serum and cerebrospinal fluid (CSF) in patients with epidemic encephalitis B rised in the primary phase, reached the maximum in the crisis phase, and falled in the recovery phase. The difference of NSE contents in the primary phase compared with it in the crisis phase in serum and CSF in all types of patients had notable statistic significance(P<0.01), and the difference of NSE contents in the recovery phase had statistic significance(P<0.05). Conclusion It is helpful for the judgement of patients′ condition with epidemic encephalitis B to measure the NSE contents.
出处
《医师进修杂志》
北大核心
2004年第10期23-24,共2页
Journal of Postgraduates of Medicine
