摘要
背景与目的:颅底囊性肿瘤的治疗原则上首选手术切除。有手术禁忌或不愿开颅手术的患者,则应选择其他治疗方法。本文探讨γ-刀治疗颅底囊性肿瘤的临床疗效。方法:使用γ-刀治疗颅底囊性肿瘤15例,肿瘤周边剂量13-16Gy(平均14Gy),中心剂量28～40Gy(平均34Gy),等剂量曲线35%～50%(平均40%),治疗靶点3～9个(平均5个),随访1～7年。结果:11例(73.3%)病灶缩小50%以上,2例(13.3%)病灶无变化,2例(13.3%)囊腔增大。结论:应用γ-刀治疗颅底囊性肿瘤,是神经外科手术治疗的有效补充。
BACKGROUND & OBJECTIVE: Operation is the first choice in the treatment of skull base cystic tumor. In the cases that cannot tolerate operation or do not prefer operation, other methods can be considered. This article aimed at evaluating the efficacy of gamma knife radiosurgery in the treatment of patients with skull base cystic tumors. METHODS: Fifteen cases of skull base cystic tumor were treated with gamma knife radiosurgery. The center dose was 34 Gy (range: 28-40 Gy). The marginal dose was 14 Gy (range: 13-16 Gy) at the 40% (range: 35%-50%) isodose line. All cases were followed up for 1 to 7 years after radiosurgery. RESULTS: The size of tumor decreased in 11 (73. 3%) cases, unchanged in 2 (13. 3%) cases, enlarged in 2 (13. 3%) cases. CONCLUSION: Gamma knife treatment is an effective complement neurosurgery, and could improve the life quality of patients with skull base cystic tumor.
出处
《中国神经肿瘤杂志》
2004年第2期99-101,共3页
Chinese Journal of Neuro-Oncology
