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双黄连注射剂致过敏性休克43例分析 被引量:21

Analysis of 43 Cases of Allergic Shock Caused by Shuang Huanglian Injection
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摘要 目的 :探讨双黄连注射剂致过敏性休克的一般规律和特点 ,以预防或避免其重复发生 ,促进临床合理用药。方法 :用文献计量学方法对近十年来国内公开报道的 4 3例双黄连注射剂致过敏性休克病例进行整理归纳与分析。结果 :双黄连注射剂致过敏性休克与性别无关 ,与药物自身因素、药物间配伍和临床医师中医诊疗水平等各种因素有关。过敏性休克多发生于小于 2 0岁和30~ 5 9岁年龄组 ,其发生时间主要集中于用药过程中的前 30分钟以内 ,均引起患者不同程度的器官损害 ,并有 3例死亡。结论 :双黄连注射剂致过敏性休克的相关因素很多 ,且后果严重 ,临床医师、药师应对其加以重视。 OBJECTIVE:To study general rule and the characters of allergic shock caused by shuang huanglian injection, in order to prevent and avoid repeat occurrence and promote rational drug use in the clinic.METHODS: By taking literature metrologic method, 43 cases of allergic shock caused by shuang huanglian injection, which were publicly reported at home in recent 10 years, were summed up and analyzed. RESULTS: Allergic shock caused by shuang huanglian injection was not related with sex, but was related with several factors, such as drug self factors, drug compatibility and doctors’level in diagnosis and treatment of traditional Chinese medicine. Allergic shock usually occurred in the people at the age of less than 20 and 30 to 59 years old. It mainly occurred 30 minutes after injecting the drug. Organ damagement of different degree of the patients was found and three patients died. CONCLUSION: There are many correlated factors with allergic shock caused by shuang huanglian injection, and the consequence is very serious. So doctors and pharmacists should pay more attention to it.
作者 曾聪彦
出处 《中国医院用药评价与分析》 2004年第4期241-243,共3页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 双黄连注射剂 过敏性休克 药物不良反应 中药制剂 shuang huanglian injection allergic shock rational drug use analysis of literature
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