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同型半胱氨酸与心脑血管疾病的相关研究 被引量:2

The total homocysteine concentration in the patient with cardiovascular and cerebralvascular disease.
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摘要 目的 研究血浆HCY水平与心脑血管疾病的关系。 方法 应用高效液相色谱法测定心脑血管疾病患者和健康体检者空腹血浆HCY水平。 结果 心脑血管疾病患者及各型血浆HCY水平明显高于对照组 (P <0 0 1) ,冠心病各型之间的血浆HCY有差异 (P <0 0 5 ) ,血浆HCY随冠心病的加重而加重 ,脑血管病类型与血浆HCY水平无关(p >0 0 5 )。 结论 HCY是心脑血管疾病的危险因素 ,其水平随着冠心病程度加重而增加 。 Objective To investigate the relationship between the levels of plasma homocysteine(HCY) and the cardiovascular and cerebralvascular disease. Method The levels of HCY in cases with cardiovascular and cerebralvascular disease and healthy people were observed by high performance liquid chromatography ( HPLC). Results The levels of HCY were higher in coronary heart disease(CHD)and cerebral vasculardisease and the types of them than those of controls(P<0.05), they were higher in old myocardial infarction than in non stable angina, and the non stable angina were higher than in stable angina pectoris(P<0.05).In the types of cerebral vascular disease, the levels of HCY is no difference(P>0.05). and it was no difference in the types of cerebral vascular disease. Conclusion HCY was the risk factor of CHD and cerebralvascular disease. The types of CHD were related to HCY, the more serious of the patient conditions of CHD is, and the higher of HCY concentrations will be. The levels of HCY had no difference among the types of cerebral vascular disease.
出处 《中国热带医学》 CAS 2004年第4期535-537,共3页 China Tropical Medicine
关键词 同型半胱氨酸 心脑血管疾病 冠心病 纤维蛋白 氧自由基 Homocysteine Coronary heart disease Cerebralvascular disease
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