摘要
目的:结合我们的病例,分析艾滋病合并荚膜组织胞浆茵病的实验室诊断特征,探讨早期初步诊断荚膜组织胞浆菌病的方法。方法:取血涂片、骨髓涂片用瑞氏染色,镜检分析所见病原体的形态特征。并用电脑图像放大辨认;抽血做血培养确诊;用血清学进一步鉴定。结果:电脑图像放大可清楚看到血涂片、骨髓涂片中有圆形、卵圆形的病原体,病原体有夹膜,无动基体,可见芽生现象,考虑是荚膜组织胞浆茵;血培养可见典型的齿轮状的厚壁分生孢子,证实涂片所见的病原体是荚膜组织胞浆茵;血清学显示AIDS抗体阳性。结论:电脑图像放大仔细鉴别血涂片、骨髓涂片所见病原体形态特征,可早于血培养15—20 d得出荚膜组织胞浆菌的初步诊断,这对临床及早制定治疗方案很有帮助。
Objective:To analyze the laboratory diagnosis character of dissemination histoplasma capsulatum secondary to AIDS,and to establish an effective way for early diagnosis of histoplasma capsulatum. Methods;The character of pathogen, which was in the patient's bone marrow and blood smears, were analyzed under microscope. For better view, the images were amplified with computer. Besides, hemoculture and serological identification to were done confirm the diagnosis. Results; The pathogen in amplified picture showed capsulatum but no kinetoplast. The macrocoridium cogwheel were observed under microscope after hemoculture. Serological identification showed positive AIDS antibody. Conclution;The detection of the pathogen's character, using computer amplification could provide tentative diagnosis of histoplasma capsulatum 15 ~20 days earlier than hemoculture; and that is helpful to therapy.
出处
《广州医学院学报》
2003年第4期52-55,共4页
Academic Journal of Guangzhou Medical College
关键词
外周血
骨髓
组织胞浆菌
blood
bone marrow
histoplasma capsulatum
