摘要
目的 从血液流变学角度研究银屑胶囊治疗银屑病的药理作用。方法 采用注射肾上腺素——冰水浴法制作大鼠急性血瘀模型,观察对血液流变学指标的影响。结果 银屑胶囊1.8 g/kg及0.6g/kg灌胃,连续给药13d,均可使急性血瘀模型大鼠的全血高切粘度、全血低切粘度、全血高切还原粘度及血浆粘度显著减小。结论 银屑胶囊可降低急性血瘀模型大鼠的全血高切粘度、全血低切粘度、全血高切还原粘度及血浆粘度,改善血液流变性,有活血化瘀作用。
Objective To observe effect of Yin-xie capsule on hemorheological parameters in acute blood stasis model rats. Methods Adr was administered to SD rats by subcutaneous,and immersed in icy water,observed the changes of hemorbeological parameters. Results Yin-xie capsule(0. 6,1. 8 g · kg-1 ,ig) could significantly decrease the whole blood HSV.the whole blood LSV.the whole blood high shear reduced viscosity and the blood plasma viscosity. These results suggest that Yin-Xie capsule can activate blood circulation and remove blood stasis. Yin-xie capsule (0.6,1. 8 g · kg-1 ,ig)could significantly decrease the whole blood HSV,the whole blood LSV, the whole blood high shear reduced viscosity and the blood plasma viscosity. Conclusion Yin-xie capsule can activate blood circulation and remove blood stasis.
出处
《广东药学》
2003年第6期30-32,共3页
Guangdong Pharmaceutical Journal
