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钛膜引导种植体周围组织再生的形态学初探 被引量:3

Morphologic Study of Guided Tissue Regeneration around Implant by Titanium Membrane
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摘要 选择6只新西兰大耳白兔,在其每根股骨的中段制备两个直径3mm的骨缺损,植入1.5Xllmm的圆柱状钛钟植体,使种植体与原合之间形成一定间隙,在其中一个种植体表面覆盖钛膜,另一个不覆盖作为对照。并在种植区邻近肌肉内将钛膜常规埋植。分别于术后2,3,4周处死动物,作肉眼、光镜观察。结果表明:肌肉内钛膜植入区无炎性反应,其周围的纤维组织结构及细胞随时间增加而成熟术膜覆盖的种植体周围无来自种植窝外的纤维组织,而在无钛膜覆盖的种植体周围,种植窝外的纤维组织向间隙内生长;与对照部位的同期相比,实验部位的种植体周围的成骨反应较明显,在骨皮质表面及内侧的新骨生长较早、较快。说明钛膜有引导组织再生的作用。 The bone holes of 3mm in diameter were created on the femur of 6 New Zealand white rahbits and l2 tita-nium cylinder implants of l1mm in length and l. 5mm in diameter inserted in the holes. Afer the placement ofeach implan, space was formed between the implants and bone. Titanium membrane was fixed on the implantand under the periosteum on one femur of animal and without titanium membrane on the other femur as con-trol. The response of muscle to titaniurn membrane was also studied. Results showed that the inteffoce be-tweeen the membrane and musle displays ideal biocompatibility without inflanmation rempse and the fibertissues and cells around titanium get mature as time goes on. Fihen tissue growns into the space between theimplant and primmp bone dri out of the implant hole in control side, but the experiment side did not showthe fiber tissue in the space from out of the implant hole. The intersting finding was that the osteoplastic re-sponse arotind the implant was stronger, earlier in experiment side than in the control side. It was coneludedthat the tissue growth around implant was guided by titanium membrane.
出处 《中国口腔种植学杂志》 1997年第4期157-160,共4页 Chinese Journal of Oral Implantology
基金 卫生部优秀青年科技人才专项科研基金
关键词 钛膜 种植体 周围组织再生 形态学 titanium membrane, GTR, implant, morphology
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