摘要
对氟苯甲酰基或杂环芳酰基取代的杂环烯酮缩胺1(2)与溴乙酸乙酯反应,高产率地得到二氮杂二环[330]4或二氮杂二环[430]5衍生物。文中讨论了合成反应机理,并且对产物的结构进行了表征。研究结果提供了一种高效率合成氮杂稠环化合物的方法,产率:79%～84%。
It was found that under a neutral condition,the reaction of heterocyclic ketene aminals and ethyl bromo-acetate could give four new heterocyclic products:4a,4b,5a,5b with excellent yields.In this work, the structures of the four products were carefully proves by NMR,IR,and the elemental analysis.The investigative outcome indicated that this thesis provide a new and convenient method for the synthesis of diazaheterobicycle[n30] derivatives.The yield reached 79%～84%.
出处
《化学与粘合》
CAS
2004年第5期276-278,共3页
Chemistry and Adhesion
