摘要
An impedance response model reflecting the inhibitory effect of antibiotics on bacterial growth in biometallurgy was established. Three inhibition parameters, i.e. the maximum amount inhibitory constant of the bacterial growth(K1 ), the maximum specific growth inhibitory constant(K2 ) and the lag time inhibitory constant(K3 ), were included in the model. The influence of these parameters on the response curve was discussed in detail. By fitting experimental data towards the proposed model, three growth parameters (A, μm and λ) in the presence of antibiotics were gained and compared. The results show that the growth ability of bacteria is decreased due to the influence of antibiotics. The experimental and fitted curves have goodness-of-fit in the range of 0. 987 - 1. 008. Moreover, the kinetic growth parameters obtained from this model are closed to those from the Logistics popular growth model.These results show that the proposed model is validity to reflect the inhibitory effect of antibiotics on bacteria.
出处
《中国有色金属学会会刊：英文版》
SCIE
EI
CSCD
2004年第3期603-608,共6页
Transactions of Nonferrous Metals Society of China
基金
Doctorate Fund of the Education Ministry of China，Sci/Tech Research Project of Education Ministry of China
