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卵母细胞的成熟抑制与发育潜力 被引量:2

Inhibition of maturation and developmental competence in oocytes
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摘要 体外成熟的卵母细胞发育潜力下降与其胞质及核成熟的不同步有关 ,因此 ,抑制卵母细胞核成熟的物质引起了人们的关注。本文综述了各种卵母细胞成熟抑制剂的作用机制及应用 ,重点讨论选择性的细胞周期蛋白依赖性激酶(CDKs)抑制剂丁内酯I(BL Ⅰ )对卵母细胞的超微结构和发育潜力的影响。BL Ⅰ能可逆性抑制卵母细胞减数分裂恢复 ,有望改善卵母细胞发育至囊胚的能力。
作者 张玲 朱桂金
出处 《生殖医学杂志》 CAS 2004年第4期252-254,共3页 Journal of Reproductive Medicine
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  • 1Lagutina I,Ponderato N,Lazzari G,et al. Kinetics of oocyte maturation and subsequent development of IVF,parthenogenetic, and NT bovine embryos after meiosis inhibition with roscovitine[J]. Cloning Stem Cells, 2002,4(2):113-119. 被引量:1
  • 2Ponderato N,Lagutina I,Crotti G, et al. Bovine oocytes treated prior to in vitro maturation with a combination of butryolactone Ⅰand roscovitine at low doses maintain a normal developmental capacity[J]. Mol Reprod Dev, 2001,60(4):579-585. 被引量:1
  • 3Ponderato N,Crotti G,Turini P, et al. Embryonic and fetal development of bovine oocytes treated with a combination of butyrolactone Ⅰand roscovitine in an enriched medium prior to IVM and IVF[J]. Mol Reprod Dev, 2002,62(4):513-518. 被引量:1
  • 4Pavlok A,Kanka J,Motlik J,et al. Culture of bovine oocytes from small antral follicles in meiosis-inhibiting medium with butyrolactone Ⅰ:RNA synthesis,nucleolar morphology and meiotic competence[J]. Anim Reprod Sci, 2000,64(1~2):1-11. 被引量:1
  • 5Eppig JJ,Schroeder AC. Capacity of mouse oocytes from preantral follicles to undergo embryogenesis and development to live young after growth,maturation and fertilization in vitro[J]. Biol Reprod, 1989,41(1):268-276. 被引量:1
  • 6Hashimoto S, Minami N,Takakura R,et al. Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro[J]. Biol Reprod, 2002,66(6):1696-1701. 被引量:1
  • 7Combelles CMH,Cekleniak NA,Racowsky C,et al. Assessment of nuclear and cytoplasmic maturation in in-vitro matured human oocytes[J]. Hum Reprod, 2002,17(4):1006-1016. 被引量:1
  • 8Kitagawa M, Okabe T, Ogino H, et al. Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase[J].Oncogene, 1993,8(9):2425-2432. 被引量:1
  • 9Lonergan P, Faerge I, Hyttel PM, et al. Ultrastrucral modifications in bovine oocytes maintained in meiotic arrest in vitro using roscovitine or butyrolactone[J]. Mol Reprod Dev, 2003,64(3):369-378. 被引量:1
  • 10Anderiesz C,Fong CY,Bongso A, et al.Regulation of human and mouse oocyte maturation in vitro with 6-dimethylaminopurine[J]. Hum Reprod, 2000,15(3):379-388. 被引量:1

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